Aquaporin-4 Antibodies Are Not Related to HTLV-1 Associated Myelopathy

Aquaporin-4 Antibodies Are Not Related to HTLV-1 Associated Myelopathy

INTRODUCTION The seroprevalence of human T-cell leukemia virus type 1 (HTLV-1) is very high among Brazilians (1:200). HTLV-1 associated myelopathy or tropical spastic paraparesis (HAM/TSP) is the most common neurological complication of HTLV-1 infection. HAM/TSP can present with an acute/subacute form of longitudinally extensive myelitis, which can be confused with lesions seen in aquaporin-4 a...

HTLV-1 -associated Myelopathy

Chronic progressive spastic paraparesis occurring in tropical areas and southwest Japan is frequently associated with high antibody titers to HTLV-1 in serum and cerebrospinal fluid.12 We recently reported that T-lymphocyte alveolitis occurred in patients with HTLV-1-associated myelopathy (HAM).3 The presence of such pulmonary lesions were also described by Vernant and associates in patients wi...

Antibodies to aquaporin-1 are not present in neuromyelitis optica

HTLV-1-associated infective dermatitis and probable HTLV-1- associated myelopathy in an adolescent female*

Human T cell lymphotropic virus type 1 (HTLV-1)-associated infective dermatitis (ID) is a chronic, severe and recurrent eczema occurring during childhood in patients vertically infected with HTLV-1. HTLV-1-associated myelopathy/tropical spastic paraparesia (HAM/ TSP) is slow and progressive. We report the case of an adolescent female from a non-endemic area for HTLV-1 who presents ID and, most ...

HTLV-1-associated myelopathy/tropical spastic paraparesis with pseudohypoparathyroidism.

In many short-stature patients with human T-lymphotrophic virus type I-associated myelopathy/tropical spastic paraparesis (HAM/TSP), signs and symptoms were manifested during childhood. Successive investigations revealed 12 of 14 short-stature patients with pseudohypoparathyroidism (PHP) from the findings of short metacarpi, parathyroid hormone infusion test, immunoblotting of erythrocyte membr...